Built for science.
Designed for compliance.

improve by scinteco,
the platform for trusted analyses in pharmacometric modeling and simulation.

Every tool your team already uses runs unchanged, while data, code, execution environments and results are captured automatically.
Every analysis is reproducible, every result already carries its own record.

Request a demo See how improve works

In production at multiple top 15 global pharmaceutical companies | ISO 9001 certified | Designed for 21 CFR Part 11 | EU Annex 11 | GAMP 5

In production at multiple top 15 global pharmaceutical companies
ISO 9001 certified
Designed for 21 CFR Part 11 | EU Annex 11 | GAMP 5

newnewOct. 2026

improve in VS Code

Work in VS Code on Windows, Linux and Mac. Every execution, output and version captured automatically, without leaving your editor.

Work in VS Code on Windows, Linux and Mac. Check out a step, edit locally, push it back - every execution, output and version captured automatically, without leaving your editor.

Screenshot of the improve platform in VS Code

how it all fits together

One company.
One platform.
One ecosystem.

the company

scinteco

The Vienna-based software company behind the improve platform. Specialised in scientific IT for the pharmaceutical industry.

About scinteco

the platform

improve

The platform. One controlled, versioned environment for data, code, models and results, with audit trail, reproducibility and governance built into every analysis.

How improve works

the ecosystem

improVerse

The ecosystem. Open R packages and extensions that build on the improve platform and extend its reach into the tools and practice of the broader scientific community.

improverse.net

the problem

What happens without a governed system?

Reproducing a result
years later

Drug development programmes run for years, with analyses built by multiple people across different environments and points in time. When a result needs to be reproduced, the exact combination of data, environment and decisions exists nowhere as a single record.

Answering a regulator

When a regulator asks how a result was produced, the answer has to be complete, consistent and verifiable. Assembling scattered records into a traceable account is rarely straightforward. Gaps that seemed minor might become findings under inspection.

When an experienced modeler moves on

When an experienced modeler moves on, scripts are shared and outputs on record. The analytical reasoning rarely transfers. The next person inherits the result but not the path that led to it.

The improve platform is built for exactly these scenarios:

Run the same analysis today, next year or on a colleague's machine. You get the same result - not because you documented everything carefully, but because the improve platform captured it automatically.

Most tools version code and scripts. The improve platform captures the complete analytical record: data, code, execution environments and every decision behind the result.

NONMEM, Monolix, R, Python, SAS and the rest of your stack. You run them exactly as before. Every run now leaves a permanent scientific record without a single extra step.

The improve platform maintains a single audit trail. You work, and the improve platform records the evidence - every action timestamped, every decision attributed, every result linked to the analysis that produced it.

In most tools, compliance is your responsibility. In the improve platform it is the platform's responsibility, built from the ground up for 21 CFR Part 11.

Every person has exactly the access their role requires, down to individual datasets and analyses. The boundaries are enforced by the system, not by trust.

One record, from raw data to submission

A single record spans every phase, from first input to final submission.

01
Raw data
- Referenced, not duplicated
- Version recorded on entry
- Checked and prepared on record
02
Analysis
- NONMEM, Monolix, R, Python, SAS and more
- Lineage is preserved
- Every execution recorded
03
Review
- Roles enforced by the system
- Decisions attributed
- No self-approval
04
Submission
- Audit trail already complete
- Every result reproducible
- Report linked to every result

built for regulated environments

ISO 9001 certified · Designed for 21 CFR Part 11, EU Annex 11 and GAMP 5

Talk to us

for every role

The improve platform fits your role
and connects everyone in the process

Every model candidate, every rejected path, every parameter decision captured and navigable. You keep working in NONMEM, R, Monolix or Python.

Structured specifications, governed pipelines, versioned outputs. Every dataset traceable from raw source to final delivery, long after handoff.

SAS macros, R scripts, package versions and execution context preserved intact. Any deliverable can be reconstructed exactly as produced.

Every action by every user generates its own compliance record automatically. Audit preparation becomes a retrieval exercise, not a reconstruction project.

Single-tenant architecture, enterprise authentication, deployment in your own AWS account, with a validation framework that does most of the work.

A submission delay, an inspection finding, a scientist who leaves with knowledge no one can reconstruct. The improve platform removes the risk before it materialises.

Built for science.Designed for compliance.

improve in VS Code

One company. One platform. One ecosystem.

scinteco

improve

improVerse

What happens without a governed system?

Reproducing a result years later

Answering a regulator

When an experienced modeler moves on

The improve platform is built for exactly these scenarios:

Same result, every time

Beyond version control

Your tools, unchanged

Audit-ready

Compliance by design

Access by role, not by trust

One record, from raw data to submission

Raw data

Analysis

Review

Submission

The improve platform fits your role and connects everyone in the process

Pharmacometric Modeler

Clinical Data Programmer

Statistical Programmer

Compliance Officer

IT Team

R&D Leadership

Built for science.
Designed for compliance.

One company.
One platform.
One ecosystem.

Reproducing a result
years later

The improve platform fits your role
and connects everyone in the process